12 Methyl Gymnodimine

Trivial Names: 12-Methyl Gymnodimine
Source Organism: Alexandruim peruvianum
CAS Registry Number: 1330004-64-2
Formula: C33H47NO4
Exact Mass: 521.35
Formula Weight: 521.73
Production Method: Natural product
Storage/Shipping Conditions: This material is packaged in glass vials and is shipped with an ice pack. If prolonged storage is required, keep in a tightly sealed container at -20oC
Toxicity: Toxic

Mode of action: 12-methyl gymnodimine is a cyclic imine metabolite isolated from the marine dinoflagellate Alexandrium peruvianum 1.  The gymnodimines display fast-acting toxicity 2 and target muscarinic, acetylcholine and nicotinic receptors 3,4

Unit size: 100 µg - $ 300

1. J. L. C. Wright, et al, Tetrahedron Let. 2011, 52, 4243 – 4246
2. D. R. Tindall, et al, in Seafood Toxins, 1984, 225-240
3. D. Richard, et al, Harmful Algal Biomass 20004. Peroric, et al, Toxicol. Pharmacol. 2000, 8, 83-94