Trivial Name : Microcystin-LR
CAS Registry Number: 101043-37-2
Source Organism: Microcystis aeruginosa
Exact Mass: 994.55
Formula Weight: 995.17
Production Method: Natural product
Storage/Shipping Conditions: This material is packaged in glass vials and is shipped with an ice pack. If prolonged storage is required, keep in a tightly sealed container at -20 o C

Toxicity: Toxic; Hepatotoxin; and Possible carcinogen

Mode of action: Microcystins are cyclic hybrid non-ribosomal peptide toxins isolated from various cyanobacteria.1 Microcystins inhibit eukaryotic protein phosphatases PP1 and PP2a and are selectively transported to the liver resulting in acute liver failure and tumor promotion.2

Unit size: 100 μg - $50

Unit size: 100 µg - $50

1 (a) Carmichael, W. W. et al. Toxicon (1988) 26 , 971-973; (b) Rinehart, K. L. et al. J. Am. Chem. Soc. (1988) 110 , 8557-8558.

2 (a) MacKintosh, C. et al. FEBS Lett. (1990) 264 , 187-192; (b) Chorus, I. et al. J. Toxicol. Env. Health B (2000) 3, 323-347; (c) Zurawell, R. et al. J. Toxicol. Env. Health B (2005) 8 , 1-37.